Rheumatoid Arthritis and Hormone Replacement Therapy (HRT): A Complex and Intriguing Relationship
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Rheumatoid Arthritis (RA) is an inflammatory autoimmune condition. In this, the immune system strikes your body’s healthy cells, leading to painful swelling on the body parts that are impacted. RA primarily attacks several joints at once. Joints in the hands, knees and wrists are usually affected by RA. The leading cause of RA has still not been identified, but a few factors can increase the chances of this condition. If left untreated, RA can lead to severe harm to the joints and their near tissues.
Globally, 18 million people live with RA. About 70% of people living with RA are women, and 55% are older than 55 years. RA can be treated with medications, surgery, physical and occupational therapy, lifestyle changes and, at times, through Hormone Replacement Therapy (HRT).
What is Hormone Replacement Therapy (HRT)?
Hormone Replacement Therapy (HRT) is a medical treatment that corrects levels or boosts hormones that your body naturally produces. It’s used to approach hormonal imbalances or declines mainly due to ageing or some medical conditions. Depending on the specific hormones involved, HRT can have various applications. While HRT is not an immediate treatment for RA, it can play an assisting role in handling some symptoms, mainly for women experiencing menopause.
While the study is still ongoing regarding the use of HRT in RA, symptom relief, bone health, and joint health are some potential benefits of Hormone Replacement Therapy. For symptom relief in women with RA experiencing menopausal symptoms like hot flashes, sweating at night, and mood swings, HRT may offer relief, improving overall well-being and potentially aiding pain management. In bone health, HRT can help prevent osteoporosis, a potential concern for people with RA due to corticosteroid use and inflammation. Studies suggest oestrogen’s protective effect on bone might also influence joint health. As for joint health, the research is ongoing, and smaller studies suggest a link between oestrogen levels and joint health, with HRT potentially offering small benefits in reducing joint pain and inflammation in postmenopausal women with RA
What must be considered before taking (Hormone Replacement Therapy) HRT for RA?
Some types of HRT can increase the risk of blood clots, which is already a potential concern for people with RA. Careful evaluation and individualization of HRT are crucial. If RA is highly active, introducing HRT might not be advisable due to potential interactions with existing medications or concerns about aggravating inflammation. Certain health conditions like breast cancer or heart disease may preclude HRT use in some individuals. Hence, considering the mentioned factors is necessary before taking any step towards HRT.
Remember: RA management is a multi-faceted approach. HRT might be a part of the picture for some women, but it’s crucial to prioritize your primary RA treatment plan and discuss any potential HRT use with your healthcare professionals.
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